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RAD51 Homolog B 抗体 (AA 22-384) (APC)

This 兔 多克隆 antibody specifically detects RAD51 Homolog B in FACS. It exhibits reactivity toward 人.
产品编号 ABIN8030102
发货至: 中国
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Quick Overview for RAD51 Homolog B 抗体 (AA 22-384) (APC) (ABIN8030102)

抗原

See all RAD51 Homolog B (Rad51B) 抗体
RAD51 Homolog B (Rad51B)

适用

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宿主

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克隆类型

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多克隆

标记

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This RAD51 Homolog B antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 22-384

    原理

    Anti-RAD51L1/RAD51B Antibody APC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human RAD51L1,RAD51B shares 85.8% amino acid (aa) sequence identity with mouse RAD51L1,RAD51B.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human RAD51L1/RAD51B recombinant protein (Position: H22-F384). Human RAD51L1/RAD51B shares 85.8% amino acid (aa) sequence identity with mouse RAD51L1/RAD51B.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    RAD51 Homolog B (Rad51B)

    别名

    RAD51B

    背景

    Background: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

    Gene Full Name: RAD51 paralog B

    基因ID

    5890

    UniProt

    O15315

    途径

    DNA Damage Repair
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