RAD51 Homolog B 抗体 (AA 180-260)
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北京 101111
Quick Overview for RAD51 Homolog B 抗体 (AA 180-260) (ABIN7223904)
抗原
See all RAD51 Homolog B (Rad51B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 180-260
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原理
- Rabbit Anti-Rad51B Polyclonal Antibody
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特异性
- Rad51B Polyclonal Antibody detects endogenous levels of Rad51B protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human Rad51B at AA range: 180-260
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亚型
- IgG
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anti-RAD51 Homolog B (Rad51B) antibody
Rad51B 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (Middle Region) antibodyRad51B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 1-384) antibodyRad51B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 143-192) antibodyRad51B 适用: 人, 猴, 犬, 豚鼠, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 251-300) antibodyRad51B 适用: 人, 小鼠, 猴, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (Center) antibodyRad51B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 1-384) antibodyRad51B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 201-250) antibodyRad51B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- RAD51 Homolog B (Rad51B)
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别名
- Rad51B
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背景
- RAD51B, RAD51L1, REC2, DNA repair protein RAD51 homolog 2, R51H2, RAD51 homolog B, Rad51B, RAD51-like protein 1The protein encoded by RAD51B (RAD51 paralog B) is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of RAD51B was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
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分子量
- 45kD
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基因ID
- 5890
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UniProt
- O15315
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途径
- DNA Damage Repair
抗原
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