RAD50 抗体 (AA 1224-1312) (Fluoro647)
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北京 101111
Quick Overview for RAD50 抗体 (AA 1224-1312) (Fluoro647) (ABIN8030093)
抗原
See all RAD50 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1224-1312
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原理
- Anti-RAD50 Antibody Fluoro647 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RAD50 recombinant protein (Position: N1224-H1312).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
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别名
- RAD50
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背景
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Background: DNA repair protein RAD50, also known as RAD50, is a protein that in humans is encoded by the RAD50 gene. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
Gene Full Name: RAD50 double strand break repair protein
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基因ID
- 10111
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UniProt
- Q92878
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途径
- DNA Damage Repair, Protein targeting to Nucleus
抗原
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