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RAD50 抗体 (AA 1224-1312) (Fluoro647)

This 兔 多克隆 antibody specifically detects RAD50 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8030093
发货至: 中国
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Quick Overview for RAD50 抗体 (AA 1224-1312) (Fluoro647) (ABIN8030093)

抗原

See all RAD50 抗体
RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

适用

  • 91
  • 76
  • 44
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 96
  • 6

克隆类型

  • 82
  • 20
多克隆

标记

  • 46
  • 9
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This RAD50 antibody is conjugated to Fluoro647

应用范围

  • 77
  • 35
  • 28
  • 26
  • 21
  • 20
  • 13
  • 13
  • 11
  • 10
  • 3
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 12
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1224-1312

    原理

    Anti-RAD50 Antibody Fluoro647 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human RAD50 recombinant protein (Position: N1224-H1312).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

    别名

    RAD50

    背景

    Background: DNA repair protein RAD50, also known as RAD50, is a protein that in humans is encoded by the RAD50 gene. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.

    Gene Full Name: RAD50 double strand break repair protein

    基因ID

    10111

    UniProt

    Q92878

    途径

    DNA Damage Repair, Protein targeting to Nucleus
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