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PRKDC 抗体 (N-Term) (FITC)

The 兔 多克隆 anti-PRKDC antibody is suitable to detect PRKDC in samples from 人. It has been validated for FACS.
产品编号 ABIN8027715
发货至: 中国
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Quick Overview for PRKDC 抗体 (N-Term) (FITC) (ABIN8027715)

抗原

See all PRKDC 抗体
PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

适用

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宿主

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克隆类型

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多克隆

标记

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This PRKDC antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    N-Term

    原理

    Anti-DNA PKcs/PRKDC Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human DNA PKcs.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

    别名

    PRKDC

    背景

    Background: PRKDC (Protein Kinase DNA-Activated Catalytic Subunit), also called DNAPK, HYRC1, p350 or DNPK1, is an enzyme that in humans is encoded by the PRKDC gene. DNA-PKcs belongs to the phosphatidylinositol 3-kinase-related kinase protein family. Satoh et al. (1997) mapped the MCM4 gene to 8q11.2 by FISH. Based on the close proximity of the PRKDC and MCM4 genes, it was assumed that the PRKDC gene also maps to this location. Anderson and Lees-Miller (1992) noted that DNA-PK had been shown in vitro to phosphorylate several transcription factors, suggesting that it functions in cell homeostasis by modulating transcription. Daniel et al. (1999) demonstrated that the PRKDC protein participates in retroviral DNA integration, which is catalyzed by the viral protein integrase.

    Gene Full Name: protein kinase, DNA-activated, catalytic subunit

    Sequence Similarities: Belongs to the PI3/PI4-kinase family.

    基因ID

    5591

    UniProt

    P78527

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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