PRMT6 抗体 (AA 45-348) (Fluoro647)
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北京 101111
Quick Overview for PRMT6 抗体 (AA 45-348) (Fluoro647) (ABIN8027122)
抗原
See all PRMT6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-348
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原理
- Anti-PRMT6 Antibody Fluoro647 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PRMT6 recombinant protein (Position: Q45-D348).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))
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别名
- PRMT6
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背景
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Background: Protein arginine N-methyltransferase 6 is an enzyme that in humans is encoded by the PRMT6 gene. The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
Gene Full Name: protein arginine methyltransferase 6
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基因ID
- 55170
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UniProt
- Q96LA8
抗原
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