G6PC 抗体 (FITC)
Quick Overview for G6PC 抗体 (FITC) (ABIN753005)
抗原
See all G6PC 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- Cow, 犬, 人, 小鼠, Pig, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase alpha
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亚型
- IgG
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应用备注
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IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
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别名
- Glucose 6 phosphatase alpha
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背景
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Synonyms: glucose-6-phosphatase, catalytic subunit, GSD1, AW107337, G-6-Pase, G6Pase, G6Pase-alpha, g6pc, G6PC_HUMAN, G6PT, Glucose-6-phosphatase alpha, Glucose-6-phosphatase, GSD1a, MGC163350, MGC93613, RP23-281C18.19.
Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-i±, a second form, designated G6Pase-i², contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-i², also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-i² hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-i² may play an integral role in diabetes and glycogen storage diseases (GSDs).
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分子量
- 40kDa
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基因ID
- 2538
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途径
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
抗原
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