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G6PC 抗体 (N-Term)

G6PC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2781770
发货至: 中国
  • 抗原 See all G6PC 抗体
    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 5
    • 1
    N-Term
    适用
    • 37
    • 18
    • 17
    • 15
    • 14
    • 13
    • 1
    • 1
    • 1
    宿主
    • 37
    • 1
    克隆类型
    • 37
    • 1
    多克隆
    标记
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This G6PC antibody is un-conjugated
    应用范围
    • 29
    • 19
    • 14
    • 11
    • 11
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    NLVFKWILFG QRPYWWVLDT DYYSNTSVPL IKQFPVTCET GPGSPSGHAM
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against G6PC. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human G6PC
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 357 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and may contain up to 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Iwasa, Kobayashi, Mifuji-Moroka, Hara, Miyachi, Sugimoto, Tanaka, Fujita, Gabazza, Takei: "Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis." in: PLoS ONE, Vol. 8, Issue 7, pp. e70309, (2013) (PubMed).

  • 抗原
    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
    别名
    G6PC (G6PC 产品)
    别名
    AW107337 antibody, G6Pase antibody, G6pt antibody, Glc-6-Pase antibody, G6PC1 antibody, G6PT antibody, GSD1 antibody, GSD1a antibody, G-6-Pase antibody, glucose-6-phosphatase, catalytic antibody, glucose-6-phosphatase catalytic subunit antibody, glucose-6-phosphatase, catalytic subunit antibody, G6pc antibody, G6PC antibody
    背景
    G6PC hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: G6PT, GSD1a, MGC163350, GSD1, G6PC1
    Protein Interaction Partner: NSL1, SNX13, CDH16, FOXO1,
    Protein Size: 357
    分子量
    40 kDa
    基因ID
    2538
    NCBI登录号
    NM_000151, NP_000142
    UniProt
    P35575
    途径
    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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