G6PC 抗体 (N-Term)
(3 references)-
- 抗原 See all G6PC 抗体
- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
-
抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This G6PC antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- DFGIQSTRYL QVNYQDSQDW FILVSVIADL RNAFYVLFPI WFHLKETVGI
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 85%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against G6pc. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product G6PC Primary Antibody
-
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (N-Term) antibody
G6PC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149) antibodyG6PC 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB30027 unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 82-117) antibodyG6PC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) antibodyG6PC 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 357 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
: "Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway." in: Molecular and cellular biochemistry, (2023) (PubMed).
: "Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates." in: Nature medicine, Vol. 23, Issue 4, pp. 439-449, (2017) (PubMed).
: "Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling." in: Nature communications, Vol. 7, pp. 10592, (2016) (PubMed).
-
: "Berberine inhibits gluconeogenesis in spontaneous diabetic rats by regulating the AKT/MAPK/NO/cGMP/PKG signaling pathway." in: Molecular and cellular biochemistry, (2023) (PubMed).
-
- 抗原
- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
- 别名
- G6pc (G6PC 产品)
- 别名
- AW107337 antibody, G6Pase antibody, G6pt antibody, Glc-6-Pase antibody, G6PC1 antibody, G6PT antibody, GSD1 antibody, GSD1a antibody, G-6-Pase antibody, glucose-6-phosphatase, catalytic antibody, glucose-6-phosphatase catalytic subunit antibody, glucose-6-phosphatase, catalytic subunit antibody, G6pc antibody, G6PC antibody
- 背景
-
G6pc hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.
Alias Symbols: AW107337, G6Pase, G6pt, Glc-6-Pase
Protein Interaction Partner: Ppargc1a, Foxo1, Sirt1,
Protein Size: 357 - 分子量
- 40 kDa
- 基因ID
- 14377
- NCBI登录号
- NM_008061, NP_032087
- UniProt
- P35576
- 途径
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
-
