G6PC 抗体
(1 reference)Quick Overview for G6PC 抗体 (ABIN752998)
抗原
See all G6PC 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- Cow, 犬, 人, 小鼠, Pig, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase alpha
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亚型
- IgG
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anti-Glucose 6-Phosphatase, Catalytic (G6PC) (N-Term) antibody
G6PC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 123-149) antibodyG6PC 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB30027 unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (N-Term) antibodyG6PC 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (N-Term) antibodyG6PC 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) (AA 82-117) antibodyG6PC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucose 6-Phosphatase, Catalytic (G6PC) antibodyG6PC 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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: "Role of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validation." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 10, pp. 2689-700, (2013) (PubMed).
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: "Role of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: from proteomic discovery to physiological validation." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 10, pp. 2689-700, (2013) (PubMed).
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- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
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别名
- Glucose 6 phosphatase alpha
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背景
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Synonyms: glucose-6-phosphatase, catalytic subunit, GSD1, AW107337, G-6-Pase, G6Pase, G6Pase-alpha, g6pc, G6PC_HUMAN, G6PT, Glucose-6-phosphatase alpha, Glucose-6-phosphatase, GSD1a, MGC163350, MGC93613, RP23-281C18.19.
Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-i±, a second form, designated G6Pase-i², contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-i², also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-i² hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-i² may play an integral role in diabetes and glycogen storage diseases (GSDs).
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分子量
- 40kDa
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基因ID
- 2538
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途径
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
抗原
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