Prostate Specific Antigen 抗体 (AA 25-261) (HRP)
Our Local Distributor
北京 101111
Quick Overview for Prostate Specific Antigen 抗体 (AA 25-261) (HRP) (ABIN8026453)
抗原
See all Prostate Specific Antigen (PSA) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 25-261
-
原理
- Anti-Prostate Specific Antigen/KLK3 Antibody HRP Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- Human PSA shares 54% amino acid (aa) sequence identity with rat PSA.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PSA recombinant protein (Position: I25-P261). Human PSA shares 54% amino acid (aa) sequence identity with rat PSA.
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- Prostate Specific Antigen (PSA)
-
别名
- KLK3
-
背景
-
Background: Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. KLK3 is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. This gene is mapped to 19q13.33. KLK3 is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. KLK3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving the cervical mucous cap, allowing the entry of sperm. It is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia.
Gene Full Name: kallikrein related peptidase 3
Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.
-
基因ID
- 354
-
UniProt
- P07288
-
途径
- Complement System
抗原
-