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POU2AF1 抗体 (C-Term) (Cy3)

The 兔 多克隆 anti-POU2AF1 antibody is suitable to detect POU2AF1 in samples from 大鼠 和 小鼠. It has been validated for FACS.
产品编号 ABIN8024817
发货至: 中国
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Room 801-803
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Quick Overview for POU2AF1 抗体 (C-Term) (Cy3) (ABIN8024817)

抗原

See all POU2AF1 抗体
POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

适用

  • 130
  • 31
  • 18
大鼠, 小鼠

宿主

  • 101
  • 54
  • 2

克隆类型

  • 81
  • 76
多克隆

标记

  • 69
  • 9
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This POU2AF1 antibody is conjugated to Cy3

应用范围

  • 105
  • 74
  • 58
  • 31
  • 30
  • 26
  • 26
  • 20
  • 18
  • 12
  • 12
  • 6
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 46
    • 16
    • 15
    • 15
    • 12
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-BOB1/POU2AF1 Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat sequence by one amino acid,and from human sequence by four amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse BOB1, different from the related rat sequence by one amino acid, and from human sequence by four amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

    别名

    POU2AF1

    背景

    Background: POU2AF1 (POU domain class 2-associating factor 1), also known as OBF1, BOB1 and OCAB, is a protein that in humans is encoded by the POU2AF1 gene. POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA. The versatility of POU protein operation is additionally conferred at the dimerization level. Casellas et al. (2002) reported that OCAB is essential for V (D)J recombination of a subset of Ig-kappa genes. They showed that OCAB modulates recombination by ly enhancing Ig-kappa gene transcription in vivo. Siegel et al. (2006) suggested that, together with dysregulation of other OCAB target genes, altered regulation of SYK may help explain the magnitude of defects observed in B-cell development, including the pre-B1-to-pre-B2 transition, and immune responses in Ocab -/- mice.

    Gene Full Name: POU domain, class 2, associating factor 1

    基因ID

    18985

    UniProt

    Q64693
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