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PAI1 抗体 (AA 24-240) (Fluoro488)

The Fluoro488-conjugated 兔 多克隆 anti-PAI1 antibody (ABIN8022859) specifically detects PAI1 in FACS. The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN8022859
发货至: 中国
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Quick Overview for PAI1 抗体 (AA 24-240) (Fluoro488) (ABIN8022859)

抗原

See all PAI1 (SERPINE1) 抗体
PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PAI1 antibody is conjugated to Fluoro488

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 24-240

    原理

    Anti-PAI1/Serpine1 Antibody Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived rat PAI1 recombinant protein (Position: S24-D240).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

    别名

    Serpine1

    背景

    Background: Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitoror serpin E1 is a protein that in humans is encoded by the SERPINE1 gene. This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: serpin family E member 1

    基因ID

    5054

    UniProt

    P20961

    途径

    p53 Pathway, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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