Plakophilin 2 抗体 (C-Term)
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Quick Overview for Plakophilin 2 抗体 (C-Term) (ABIN8022800)
抗原
See all Plakophilin 2 (PKP2) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Anti-Plakophilin 2/PKP2 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- identical to the related mouse sequence,and different from the related rat sequence by one amino acid.
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产品特性
- Anti-Plakophilin 2/PKP2 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Plakophilin 2, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Plakophilin 2 (PKP2)
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别名
- PKP2
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背景
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Background: Plakophilin-2 is a protein that in humans is encoded by the PKP2 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. It is mapped to 12p11.21. PKP2 is a constituent of the desmosomal plaque in simple epithelia, some stratified epithelia, and some nonepithelial cells. PKP2 is also enriched in the karyoplasm of cells of various types, including those lacking desmosomes. Plakophilin proteins participate in linking cadherins to intermediate filaments in the cytoskeleton and this gene product may regulate the signaling activity of beta-catenin. PKP2 has been shown to interact with Desmoplakin, Plakoglobin and Desmoglein 1.
Gene Full Name: plakophilin 2
Sequence Similarities: Belongs to the beta-catenin family.
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分子量
- 97 kDa
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基因ID
- 5318
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UniProt
- Q99959
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途径
- Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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