PEX5 抗体 (Middle Region) (FITC)
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北京 101111
Quick Overview for PEX5 抗体 (Middle Region) (FITC) (ABIN8020778)
抗原
See all PEX5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-PEX5 Antibody FITC Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human PEX5 shares 95.7% amino acid (aa) sequence identity with both mouse,rat PEX5.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PEX5. Human PEX5 shares 95.7% amino acid (aa) sequence identity with both mouse and rat PEX5.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))
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别名
- PEX5
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背景
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Background: The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Full Name: peroxisomal biogenesis factor 5
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基因ID
- 5830
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UniProt
- P50542
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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