NHEJ1 抗体 (AA 1-273) (Fluoro550)
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北京 101111
Quick Overview for NHEJ1 抗体 (AA 1-273) (Fluoro550) (ABIN8016092)
抗原
See all NHEJ1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-273
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原理
- Anti-XLF/NHEJ1 Antibody Fluoro550 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human XLF/NHEJ1 recombinant protein (Position: M1-E273).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))
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别名
- NHEJ1
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背景
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Background: Non-homologous end-joining factor 1 (NHEJ1), also known as Cernunnos or XRCC4-like factor (XLF), is a protein that in humans is encoded by the NHEJ1 gene. It is mapped to 2q35. Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
Gene Full Name: non-homologous end joining factor 1
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基因ID
- 79840
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UniProt
- Q9H9Q4
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途径
- DNA Damage Repair
抗原
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