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NLRP6 抗体 (AA 14-887) (APC)

The 兔 多克隆 anti-NLRP6 antibody is suitable to detect NLRP6 in samples from 人. It has been validated for FACS.
产品编号 ABIN8015919
发货至: 中国
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Room 801-803
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Quick Overview for NLRP6 抗体 (AA 14-887) (APC) (ABIN8015919)

抗原

See all NLRP6 抗体
NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

适用

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宿主

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克隆类型

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多克隆

标记

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This NLRP6 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 14-887

    原理

    Anti-NLRP6 Antibody APC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human NLRP6 shares 71.7%,72.9% amino acid (aa) sequence identity with mouse,rat NLRP6,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human NLRP6 recombinant protein (Position: R14-E887). Human NLRP6 shares 71.7% and 72.9% amino acid (aa) sequence identity with mouse and rat NLRP6, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

    别名

    NLRP6

    背景

    Background: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: NLR family pyrin domain containing 6

    基因ID

    171389

    UniProt

    P59044

    途径

    Inflammasome
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