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NBR1 抗体 (AA 1-665) (Cy3)

The 兔 多克隆 anti-NBR1 antibody is suitable to detect NBR1 in samples from 人 和 猴. It has been validated for FACS.
产品编号 ABIN8014197
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NBR1 抗体 (AA 1-665) (Cy3) (ABIN8014197)

抗原

See all NBR1 抗体
NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

适用

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人, 猴

宿主

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克隆类型

  • 29
  • 12
多克隆

标记

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This NBR1 antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1-665

    原理

    Anti-NBR1 Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human NBR1 recombinant protein (Position: M1-H665).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

    别名

    NBR1

    背景

    Background: Neighbor of BRCA1 gene 1 protein is a protein that in humans is encoded by the NBR1 gene. The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.

    Gene Full Name: NBR1 autophagy cargo receptor

    基因ID

    4077

    UniProt

    Q14596

    途径

    Autophagy
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