MYD88 抗体 (AA 12-263) (Cy3)
Our Local Distributor
北京 101111
Quick Overview for MYD88 抗体 (AA 12-263) (Cy3) (ABIN8012435)
抗原
See all MYD88 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 12-263
-
原理
- Anti-MyD88 Antibody Cy3 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived mouse MyD88 recombinant protein (Position: S12-D263).
-
亚型
- IgG
-
-
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 201-296) antibody
MYD88 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IP, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 44-264) antibodyMYD88 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 32-265) antibodyMYD88 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (Internal Region) antibodyVerified MYD88 适用: 人 WB, IHC, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 136-164) antibodyMYD88 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21010 unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 60-309) antibodyMYD88 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) antibodyKO Validated MYD88 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
-
-
应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
-
别名
- Myd88
-
背景
-
Background: MYD88 (MYELOID DIFFERENTIATION PRIMARY RESPONSE GENE 88), is a protein that, in humans, is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL1Rs). And it is mapped on 3p22.2. MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. Overexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter. The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP. Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.
Gene Full Name: myeloid differentiation primary response gene 88
-
基因ID
- 17874
-
UniProt
- P22366
-
途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
-
