MUTYH 抗体 (AA 1-559)
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北京 101111
Quick Overview for MUTYH 抗体 (AA 1-559) (ABIN8012235)
抗原
See all MUTYH 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 1-559
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原理
- Anti-MUTYH Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human IFFO1 shares 94.1% amino acid (aa) sequence identity with mouse IFFO1.
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产品特性
- Anti-MUTYH Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IFFO1 recombinant protein (Position: M1-R559). Human IFFO1 shares 94.1% amino acid (aa) sequence identity with mouse IFFO1.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- MUTYH (MutY Homolog (E. Coli) (MUTYH))
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别名
- MUTYH
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背景
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Background: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: mutY DNA glycosylase
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分子量
- 60 kDa
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基因ID
- 4595
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UniProt
- Q9UIF7
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途径
- DNA Damage Repair
抗原
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