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MUTYH 抗体 (AA 1-559)

The 兔 多克隆 anti-MUTYH antibody is suitable to detect MUTYH in samples from 人 和 大鼠. It has been validated for WB, ELISA 和 FACS.
产品编号 ABIN8012235
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MUTYH 抗体 (AA 1-559) (ABIN8012235)

抗原

See all MUTYH 抗体
MUTYH (MutY Homolog (E. Coli) (MUTYH))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MUTYH antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

质量等级

Carrier-free
  • 抗原表位

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    AA 1-559

    原理

    Anti-MUTYH Antibody

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human IFFO1 shares 94.1% amino acid (aa) sequence identity with mouse IFFO1.

    产品特性

    Anti-MUTYH Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human IFFO1 recombinant protein (Position: M1-R559). Human IFFO1 shares 94.1% amino acid (aa) sequence identity with mouse IFFO1.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    MUTYH (MutY Homolog (E. Coli) (MUTYH))

    别名

    MUTYH

    背景

    Background: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: mutY DNA glycosylase

    分子量

    60 kDa

    基因ID

    4595

    UniProt

    Q9UIF7

    途径

    DNA Damage Repair
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