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MUTYH 抗体 (AA 1-559) (HRP)

This 兔 多克隆 antibody specifically detects MUTYH in WB, ELISA 和 IHC. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN8012231
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MUTYH 抗体 (AA 1-559) (HRP) (ABIN8012231)

抗原

See all MUTYH 抗体
MUTYH (MutY Homolog (E. Coli) (MUTYH))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MUTYH antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-559

    原理

    Anti-MUTYH Antibody HRP Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human IFFO1 shares 94.1% amino acid (aa) sequence identity with mouse IFFO1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human IFFO1 recombinant protein (Position: M1-R559). Human IFFO1 shares 94.1% amino acid (aa) sequence identity with mouse IFFO1.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    MUTYH (MutY Homolog (E. Coli) (MUTYH))

    别名

    MUTYH

    背景

    Background: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: mutY DNA glycosylase

    基因ID

    4595

    UniProt

    Q9UIF7

    途径

    DNA Damage Repair
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