MUC5AC 抗体 (AA 4848-5030)
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Quick Overview for MUC5AC 抗体 (AA 4848-5030) (ABIN8011938)
抗原
See all MUC5AC 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 4848-5030
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原理
- Anti-Mucin 5AC/MUC5AC Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Mucin 5AC/MUC5AC Antibody. Tested in IHC applications. This antibody reacts with Human, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Mucin 5AC recombinant protein (Position: D4848-H5030).
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亚型
- IgG
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
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别名
- MUC5AC
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背景
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Background: Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. MUC5AC is also a and critical mediator of resistance during intestinal nematode infection.
Gene Full Name: mucin 5AC, oligomeric mucus/gel-forming
Sequence Similarities: Contains 1 CTCK (C-terminal cystine knot-like) domain.
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分子量
- 585 kDa
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基因ID
- 4586
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UniProt
- P98088
抗原
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