MAP3K2 抗体 (C-Term) (FITC)
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Quick Overview for MAP3K2 抗体 (C-Term) (FITC) (ABIN8011284)
抗原
See all MAP3K2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-MEKK2/MAP3K2 Antibody FITC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related rat,mouse sequences by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MEKK2, different from the related rat and mouse sequences by one amino acid.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) antibody
MAP3K2 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 4B4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) antibodyKD Validated MAP3K2 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB260 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 14-43), (N-Term) antibodyMAP3K2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34479 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 111-200) antibodyMAP3K2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 357-619) antibodyMAP3K2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 1-364) antibodyMAP3K2 适用: 人, 大鼠 WB, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (C-Term) antibodyMAP3K2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) (AA 146-195) antibodyMAP3K2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
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别名
- MAP3K2
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背景
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Background: MAP3K2, mitogen-activated protein kinase kinase kinase 2, also known as MEKK2, belongs to the mitogen-activated protein kinase (MAPK) kinase kinase gene family, which is involved in regulating multiple MAPK signaling pathways. Endogenous MAP3K2 localized mainly to the cytosol of unstimulated HeLa cells and rat fibroblasts. The MAP3K2 gene is mapped to chromosome 2 by the International Radiation Hybrid Mapping Consortium. MAP3K2 is a major upstream activator of the JNK, MAPK cascade. MAP3K2 was identifies as 1 of 6 kinases that regulate different steps of the caveolar cycle. Silencing of MAP3K2 strongly reduced kiss-and-run dynamics, leading to an accumulation of caveolar structures at the cell surface without affecting caveolae coat assembly or clustering.
Gene Full Name: mitogen-activated protein kinase kinase kinase 2
Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
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基因ID
- 10746
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UniProt
- Q9Y2U5
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途径
- MAPK Pathway
抗原
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