MSH2 抗体 (AA 337-583)
Our Local Distributor
北京 101111
Quick Overview for MSH2 抗体 (AA 337-583) (ABIN8010607)
抗原
See all MSH2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- AA 337-583
-
原理
- Anti-MSH2 Antibody (monoclonal, 6B4F7)
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
预测反应
- Human MSH2 shares 94%,93% amino acid (aa) sequence identity with mouse,rat MSH2,respectively.
-
产品特性
- Anti-MSH2 Antibody.(monoclonal, 6B4F7)-5. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human MSH2 recombinant protein (Position: Q337-N583). Human MSH2 shares 94% and 93% amino acid (aa) sequence identity with mouse and rat MSH2, respectively.
-
亚型
- IgG2b
-
-
-
-
应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
-
-
- MSH2 (Mismatch Repair Protein 2 (MSH2))
-
别名
- MSH2
-
背景
-
Background: DNA mismatch repair protein Msh2, also known as MutS protein homolog 2 or MSH2, is a protein that in humans is encoded by the MSH2 gene, which is located on chromosome 2. MSH2 is a tumor suppressor gene and more specifically a caretaker gene that codes for a DNA mismatch repair (MMR) protein, MSH2 which forms aheterodimer with MSH6 to make the human MutSα mismatch repair complex. It also dimerizes with MSH3 to form the MutSβ DNA repair complex. MSH2 is involved in many different forms of DNA repair, including transcription-coupled repair, homologous recombination, and base excision repair. It has been found that MSH2 may also be a coactivator of ESR1-dependent gene expression.
Gene Full Name: mutS homolog 2
-
分子量
- 105 kDa
-
基因ID
- 4436
-
UniProt
- P43246
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-