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MSH2 抗体 (AA 337-583) (Fluoro647)

The 小鼠 单克隆 anti-MSH2 antibody is suitable to detect MSH2 in samples from 人. It has been validated for FACS.
产品编号 ABIN8010606
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MSH2 抗体 (AA 337-583) (Fluoro647) (ABIN8010606)

抗原

See all MSH2 抗体
MSH2 (Mismatch Repair Protein 2 (MSH2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MSH2 antibody is conjugated to Fluoro647

应用范围

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Flow Cytometry (FACS)

克隆位点

6B4F7
  • 抗原表位

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    AA 337-583

    原理

    Anti-MSH2 Antibody (monoclonal, 6B4F7) Fluoro647 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human MSH2 shares 94%,93% amino acid (aa) sequence identity with mouse,rat MSH2,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MSH2 recombinant protein (Position: Q337-N583). Human MSH2 shares 94% and 93% amino acid (aa) sequence identity with mouse and rat MSH2, respectively.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    MSH2 (Mismatch Repair Protein 2 (MSH2))

    别名

    MSH2

    背景

    Background: DNA mismatch repair protein Msh2, also known as MutS protein homolog 2 or MSH2, is a protein that in humans is encoded by the MSH2 gene, which is located on chromosome 2. MSH2 is a tumor suppressor gene and more specifically a caretaker gene that codes for a DNA mismatch repair (MMR) protein, MSH2 which forms aheterodimer with MSH6 to make the human MutSα mismatch repair complex. It also dimerizes with MSH3 to form the MutSβ DNA repair complex. MSH2 is involved in many different forms of DNA repair, including transcription-coupled repair, homologous recombination, and base excision repair. It has been found that MSH2 may also be a coactivator of ESR1-dependent gene expression.

    Gene Full Name: mutS homolog 2

    基因ID

    4436

    UniProt

    P43246

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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