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MBD2 抗体 (AA 159-411) (HRP)

This 兔 多克隆 antibody specifically detects MBD2 in WB, IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN8009579
发货至: 中国
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Quick Overview for MBD2 抗体 (AA 159-411) (HRP) (ABIN8009579)

抗原

See all MBD2 抗体
MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

适用

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宿主

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克隆类型

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多克隆

标记

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This MBD2 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 159-411

    原理

    Anti-MBD2 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human MBD2 shares 98% amino acid (aa) sequence identity with mouse MBD2.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MBD2 recombinant protein (Position: W159-A411). Human MBD2 shares 98% amino acid (aa) sequence identity with mouse MBD2.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

    别名

    MBD2

    背景

    Background: Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene. It is mapped to 18q21.2. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.

    Gene Full Name: methyl-CpG binding domain protein 2

    Sequence Similarities: Contains 1 MBD (methyl-CpG-binding) domain.

    基因ID

    8932

    UniProt

    Q9UBB5

    途径

    Chromatin Binding
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