MBD2 抗体 (AA 159-411) (Fluoro550)
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Quick Overview for MBD2 抗体 (AA 159-411) (Fluoro550) (ABIN8009576)
抗原
See all MBD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 159-411
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原理
- Anti-MBD2 Antibody Fluoro550 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human MBD2 shares 98% amino acid (aa) sequence identity with mouse MBD2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MBD2 recombinant protein (Position: W159-A411). Human MBD2 shares 98% amino acid (aa) sequence identity with mouse MBD2.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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别名
- MBD2
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背景
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Background: Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene. It is mapped to 18q21.2. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.
Gene Full Name: methyl-CpG binding domain protein 2
Sequence Similarities: Contains 1 MBD (methyl-CpG-binding) domain.
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基因ID
- 8932
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UniProt
- Q9UBB5
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途径
- Chromatin Binding
抗原
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