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MASP2 抗体 (C-Term) (Fluoro594)

The Fluoro594-conjugated 兔 多克隆 anti-MASP2 antibody (ABIN8007652) specifically detects MASP2 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN8007652
发货至: 中国
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Quick Overview for MASP2 抗体 (C-Term) (Fluoro594) (ABIN8007652)

抗原

See all MASP2 抗体
MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

适用

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宿主

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克隆类型

  • 64
  • 9
多克隆

标记

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This MASP2 antibody is conjugated to Fluoro594

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-MASP2 Antibody Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human MASP2, which shares 88% and 76% amino acid (aa) sequence identity with mouse and rat MASP2, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

    别名

    MASP2

    背景

    Background: Mannan-binding lectin serine protease 2 is a protein that in humans is encoded by the MASP2 gene. This gene is mapped to 1p36.22. This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

    Gene Full Name: MBL associated serine protease 2

    基因ID

    10747

    UniProt

    O00187

    途径

    Complement System
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