Lamin B2 抗体 (C-Term) (Fluoro488)
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Quick Overview for Lamin B2 抗体 (C-Term) (Fluoro488) (ABIN8005041)
抗原
See all Lamin B2 (LMNB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Lamin B2/LMNB2 Antibody Fluoro488 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Lamin B2, identical to the related rat and mouse sequences.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Lamin B2 (LMNB2)
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别名
- LMNB2
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背景
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Background: Lamin B2, also called LMNB2, is a protein associated with laminopathies. The LMNB2 gene is mapped to the G-negative subtelomeric band p13.3 of chromosome 19 by in situ hybridization. The LMNB2 gene contains 12 exons. < a href=https://www.bosterbio.com/blog/post/how-to-choose-a-model-organism style=color:#EA8D28>Common model organisms have been used in the study of Lamin B2 function. A conditional knockout mouse line, called Lmnb2, is generated as part of the International Knockout Mouse Consortium program-a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. A highly sensitive procedure about mapping the start site of DNA replication in a 13.7-kb region of human chromosome 19 coding for lamin B2 is developed for the identification of the origin of biional DNA synthesis in single-copy replicons of mammalian cells.
Gene Full Name: lamin B2
Sequence Similarities: Belongs to the intermediate filament family.
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基因ID
- 84823
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UniProt
- Q03252
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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