Lamin B2 抗体 (AA 128-585) (Biotin)
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Quick Overview for Lamin B2 抗体 (AA 128-585) (Biotin) (ABIN8005028)
抗原
See all Lamin B2 (LMNB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 128-585
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原理
- Anti-Lamin B2/LMNB2 Antibody Biotin Conjugated
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预测反应
- Human LMNB2 shares 81.8% amino acid (aa) sequence identity with mouse LMNB2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Lamin B2/LMNB2 recombinant protein (Position: L128-E585). Human LMNB2 shares 81.8% amino acid (aa) sequence identity with mouse LMNB2.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Lamin B2 (LMNB2)
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别名
- Lamin B2/LMNB2
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背景
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Background: Lamin B2 is a protein that in humans is encoded by the LMNB2 gene. This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.
Gene Full Name: lamin B2
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基因ID
- 84823
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UniProt
- Q03252
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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