JUP 抗体 (AA 556-745) (Fluoro647)
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Quick Overview for JUP 抗体 (AA 556-745) (Fluoro647) (ABIN8003738)
抗原
See all JUP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 556-745
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原理
- Anti-gamma Catenin Antibody (monoclonal, 4C12D7) Fluoro647 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse,rat gamma Catenin.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human gamma Catenin recombinant protein (Position: M556-A745). Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse and rat gamma Catenin.
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亚型
- IgG1
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- JUP (Junction Plakoglobin (JUP))
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别名
- JUP
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背景
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Background: Junction plakoglobin(JUP), also known as gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to β-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Meanwhile, JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.
Gene Full Name: junction plakoglobin
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基因ID
- 3728
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UniProt
- P14923
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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