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CYBB 抗体 (AA 501-570)

Name: CYBB 抗体 (AA 501-570)
SKU: ABIN750688
Availability: OutOfStock

This anti-CYBB antibody is a 兔多克隆 antibody detecting CYBB in WB, ELISA, FACS, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠, 兔和小鸡. This Primary Antibody has been cited in 6+ publications.

Mouse spleen lysates probed with NOX2/gp91phox Polyclonal Antibody, unconjugated at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 60 minutes at 37°C. (CYBB 抗体 (AA 501-570))

Formalin-fixed and paraffin embedded rat pancreas labeled with Anti NOX2/gp91phox Polyclonal Antibody, Unconjugated (ABIN750688) at 1:200 followed by conjugation to the secondary antibody and DAB staining (CYBB 抗体 (AA 501-570))

IHC

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-NOX2/gp91phox Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (CYBB 抗体 (AA 501-570))

IHC (p)

Image provided by One World Lab validation program. (CYBB 抗体 (AA 501-570))

IF (cc)

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-NOX2/gp91phox Polyclonal Antibody, Unconjugated used at 1:200 dilution for 40 minutes at 37°C. (CYBB 抗体 (AA 501-570))

IF (p)

5 images

(6 references)

产品编号 ABIN750688

发货至: 中国

Datasheet as PDF

Quick Overview for CYBB 抗体 (AA 501-570) (ABIN750688)

抗原

See all CYBB 抗体

CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

适用

人, 小鼠, 大鼠, 兔, 小鸡

宿主

兔

克隆类型

多克隆

标记

This CYBB antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

抗原表位
15

9

4

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2

1

1

1

1

1

1

1

1

1

1

1

1
AA 501-570

交叉反应

小鸡, 人, 小鼠, 兔, 大鼠

预测反应

Dog,Cow,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human NOX2/gp91phox

亚型

IgG
anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 283-570) antibody
CYBB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 283-570) antibody
CYBB 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome B-245, beta Polypeptide (CYBB) (C-Term) antibody
CYBB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome B-245, beta Polypeptide (CYBB) antibody
CYBB 适用: 人 WB, IF, IHC (p), ICC 宿主: 小鼠 Monoclonal 54-1 unconjugated

anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 442-459), (Middle Region) antibody
CYBB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 283-570) antibody
CYBB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome B-245, beta Polypeptide (CYBB) (Internal Region) antibody
Verified CYBB 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 100-200) antibody
CYBB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 416-500) antibody
CYBB 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 501-570) antibody (Biotin)
CYBB 适用: 人, 小鼠, 大鼠, 兔, 小鸡 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Ye, Wu, Liu, Chen, Zhang, Lu, Zhou, Li, Zhang, Xia, Zhuang, Hang et al.: "Inhibition of leukotriene B4 synthesis protects against early brain injury possibly via reducing the neutrophil-generated inflammatory response and oxidative stress after subarachnoid hemorrhage in ..." in: Behavioural brain research, Vol. 339, pp. 19-27, (2017) (PubMed).

Wakatsuki, Furuno, Ohshima, Araki: "Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." in: The Journal of cell biology, Vol. 211, Issue 4, pp. 881-96, (2015) (PubMed).

Kashiwabara, Ambe, Nakagawa, Watanabe: "Immunohistochemical localization of Nox in mouse circumvallate papillae." in: Tissue & cell, Vol. 47, Issue 6, pp. 550-8, (2015) (PubMed).

Wang, Li, Cheng, Zhang, Narsinh, Li, Li, Qin, Zhang, Li, Su, Chen, Cao: "Activation of Liver X Receptor Improves Viability of Adipose-Derived Mesenchymal Stem Cells to Attenuate Myocardial Ischemia Injury Through TLR4/NF-?B and Keap-1/Nrf-2 Signaling Pathways." in: Antioxidants & redox signaling, (2014) (PubMed).

Dalaklioglu, Tasatargil, Kale, Tanriover, Dilmac, Erin: "Metastatic breast carcinoma induces vascular endothelial dysfunction in Balb-c mice: Role of the tumor necrosis factor-? and NADPH oxidase." in: Vascular pharmacology, Vol. 59, Issue 3-4, pp. 103-11, (2013) (PubMed).

Lagadinou, Sach, Callahan, Rossi, Neering, Minhajuddin, Ashton, Pei, Grose, ODwyer, Liesveld, Brookes, Becker, Jordan: "BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells." in: Cell stem cell, Vol. 12, Issue 3, pp. 329-41, (2013) (PubMed).
抗原

CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

别名

NOX2/gp91phox

背景

Synonyms: CGD, NOX2, IMD34, AMCBX2, GP91-1, GP91PHOX, p91-PHOX, GP91-PHOX, Cytochrome b-245 heavy chain, CGD91-phox, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Heme-binding membrane glycoprotein gp91phox, NADPH oxidase 2, Neutrophil cytochrome b 91 kDa polypeptide, Superoxide-generating NADPH oxidase heavy chain subunit, p22 phagocyte B-cytochrome, CYBB
Background: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

基因ID

1536

UniProt

P04839