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IDH2 抗体 (C-Term) (Fluoro550)

This 小鼠 单克隆 antibody specifically detects IDH2 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8003435
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IDH2 抗体 (C-Term) (Fluoro550) (ABIN8003435)

抗原

See all IDH2 抗体
IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

适用

  • 132
  • 110
  • 100
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 83
  • 48
  • 1
小鼠

克隆类型

  • 67
  • 65
单克隆

标记

  • 47
  • 7
  • 6
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IDH2 antibody is conjugated to Fluoro550

应用范围

  • 79
  • 66
  • 38
  • 28
  • 18
  • 13
  • 13
  • 11
  • 9
  • 7
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

6B13
  • 抗原表位

    • 48
    • 16
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-IDH2 Antibody (monoclonal, 6B13) Fluoro550 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human IDH2, identical to the related mouse and rat sequences.

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

    别名

    IDH2

    背景

    Background: Isocitrate dehydrogenase [NADP], mitochondrialis anenzymethat in humans is encoded by theIDH2gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+). Five isocitrate dehydrogenases have been reported: three NAD (+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP (+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP (+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.

    Gene Full Name: isocitrate dehydrogenase (NADP(+)) 2

    基因ID

    3418

    UniProt

    P48735

    途径

    Warburg Effect
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