IDH2 抗体 (C-Term)
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北京 101111
Quick Overview for IDH2 抗体 (C-Term) (ABIN3043856)
抗原
See all IDH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-IDH2 Antibody
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序列
- KDLAGCIHGL SNVKLNEHFL NTTDFLDTIK SNLDR
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related mouse,rat sequences.
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产品特性
- Anti-IDH2 Antibody. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human IDH2, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 40-452) antibody
IDH2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 1-143) antibodyIDH2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3E8E9 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 193-452) antibodyIDH2 适用: 人 WB, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 354-451) antibodyIDH2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5F11 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (C-Term) antibodyIDH2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 小鼠 Monoclonal 6B13 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (C-Term) antibodyIDH2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 2H4 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 354-452) antibodyIDH2 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5F11 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) antibodyIDH2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 402-452) antibodyIDH2 适用: 人, 小鼠 WB, IP, IF/ICC, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 251-350) antibodyIDH2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL Immunocytochemistry/Immunofluorescence, 5 μg/mL
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
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别名
- IDH2
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背景
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Background: Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+). Five isocitrate dehydrogenases have been reported: three NAD (+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP (+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP (+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
Gene Full Name: isocitrate dehydrogenase (NADP(+)) 2
Sequence Similarities: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
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分子量
- 45 kDa
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基因ID
- 3418
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UniProt
- P48735
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途径
- Warburg Effect
抗原
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