IRF5 抗体 (AA 98-477) (HRP)
Our Local Distributor
北京 101111
Quick Overview for IRF5 抗体 (AA 98-477) (HRP) (ABIN8001282)
抗原
See all IRF5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 98-477
-
原理
- Anti-IRF5 Antibody HRP Conjugated
-
交叉反应 (详细)
- No cross reactivity with other proteins.
-
预测反应
- Human IRF5 shares 85.6% amino acid (aa) sequence identity with mouse IRF5.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human IRF5 recombinant protein (Position: R98-A477). Human IRF5 shares 85.6% amino acid (aa) sequence identity with mouse IRF5.
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- IRF5 (Interferon Regulatory Factor 5 (IRF5))
-
别名
- IRF5
-
背景
-
Background: Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.
Gene Full Name: interferon regulatory factor 5
-
基因ID
- 3663
-
UniProt
- Q13568
-
途径
- TLR signaling, Autophagy
抗原
-