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IRF5 抗体 (AA 98-477) (Fluoro488)

This 兔 多克隆 antibody specifically detects IRF5 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8001278
发货至: 中国
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Quick Overview for IRF5 抗体 (AA 98-477) (Fluoro488) (ABIN8001278)

抗原

See all IRF5 抗体
IRF5 (Interferon Regulatory Factor 5 (IRF5))

适用

  • 116
  • 80
  • 64
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 114
  • 9
  • 1
  • 1

克隆类型

  • 87
  • 38
多克隆

标记

  • 56
  • 9
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
This IRF5 antibody is conjugated to Fluoro488

应用范围

  • 76
  • 51
  • 40
  • 37
  • 24
  • 22
  • 18
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 24
    • 12
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 98-477

    原理

    Anti-IRF5 Antibody Fluoro488 Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human IRF5 shares 85.6% amino acid (aa) sequence identity with mouse IRF5.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human IRF5 recombinant protein (Position: R98-A477). Human IRF5 shares 85.6% amino acid (aa) sequence identity with mouse IRF5.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    IRF5 (Interferon Regulatory Factor 5 (IRF5))

    别名

    IRF5

    背景

    Background: Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.

    Gene Full Name: interferon regulatory factor 5

    基因ID

    3663

    UniProt

    Q13568

    途径

    TLR signaling, Autophagy
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