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Integrin beta 3 抗体 (C-Term) (Fluoro647)

The 兔 多克隆 anti-Integrin beta 3 antibody is suitable to detect Integrin beta 3 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN8000559
发货至: 中国
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北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Integrin beta 3 抗体 (C-Term) (Fluoro647) (ABIN8000559)

抗原

See all Integrin beta 3 (ITGB3) 抗体
Integrin beta 3 (ITGB3)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Integrin beta 3 antibody is conjugated to Fluoro647

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-Integrin beta 3/ITGB3 Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Integrin beta 3, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Integrin beta 3 (ITGB3)

    别名

    ITGB3

    背景

    Background: ITGB3 (INTEGRIN, BETA-3), also called GP3A, GPIIIa, CD61, is a protein that in humans is encoded by the ITGB3 gene. GP3A is a cluster of differentiation found on thrombocytes. The ITGB3 complex belongs to the integrin class of cell adhesion molecule receptors that share a common heterodimeric structure with alpha and beta subunits. The GP3A gene is mapped to 17q21.32. And the GP3A gene has 14 exons. The 3-prime exon is larger than 1,700 nucleotides and contains the 3-prime untranslated region. The ITGB3 complex mediates platelet aggregation by acting as a receptor for fibrinogen. Although the ITGB3 is expressed on the cell surface at normal levels and is capable of function following extracellular stimulation, it could not be activated via the inside-out signaling pathways.

    Gene Full Name: integrin subunit beta 3

    Sequence Similarities: Belongs to the integrin beta chain family.

    基因ID

    3690

    UniProt

    P05106

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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