IGFBP5 抗体 (N-Term)
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Quick Overview for IGFBP5 抗体 (N-Term) (ABIN8000219)
抗原
See all IGFBP5 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- N-Term
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原理
- Anti-IGFBP5 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse,rat sequences by two amino acids.
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产品特性
- Anti-IGFBP5 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human IGFBP5, different from the related mouse and rat sequences by two amino acids.
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亚型
- IgG
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anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 68-167) antibody
IGFBP5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 25-271) antibodyIGFBP5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) antibodyIGFBP5 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 101-200) antibodyIGFBP5 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 87-121) antibodyIGFBP5 适用: 人 WB 宿主: 兔 Polyclonal RB54635 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 27-248) antibodyIGFBP5 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 27-248) antibodyIGFBP5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 1-272) antibodyIGFBP5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Insulin-Like Growth Factor Binding Protein 5 (IGFBP5) (AA 111-160) antibodyIGFBP5 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, 绵羊, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA, 0.1-0.5 μg/mL, -Western blot, 0.1-0.5 μg/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- IGFBP5 (Insulin-Like Growth Factor Binding Protein 5 (IGFBP5))
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别名
- IGFBP5
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背景
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Background: Insulin-like growth factor-binding protein 5?is a?protein?that in humans is encoded by the?IGFBP5?gene. The expression of?IGFBP5?by stable transfection and adenovirus-mediated infection is inhibitory to growth in 2 human breast cancer cell lines.?IGFBP5?expression leads to G2/M cell cycle arrest and apoptosis. Stable expression of?IGFBP5?in the breast cancer cell lines also inhibits the formation and growth of tumors following injection in athymic mice. It is concluded that IGFBP5?is a growth inhibitor and proapoptotic agent in breast cancer cells. Additionally, IGFBP-5 is expressed by fibroblasts, myoblasts and osteoblasts, making it the predominant IGFBP found in bone extracts. It has a strong affinity for hydroxyapatite, allowing it to bind to bone cells. When bound to extracellular matrix, IGFBP-5 is protected from proteolysis and potentiates IGF activity, but when it is soluble, IGFBP-5 is cleaved to a biologically inactive 21? kDa fragment (1,?2).
Gene Full Name: insulin like growth factor binding protein 5
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分子量
- 23 kDa
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基因ID
- 3488
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UniProt
- P24593
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途径
- WNT signaling, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
抗原
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