HNF4A 抗体 (AA 164-474) (FITC)
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北京 101111
Quick Overview for HNF4A 抗体 (AA 164-474) (FITC) (ABIN7997193)
抗原
See all HNF4A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 164-474
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原理
- Anti-HNF-4-alpha Antibody (monoclonal, 6C8E9) FITC Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- Human HNF-4-alpha shares 95%,96% amino acid (aa) sequence identity with mouse,rat HNF-4-alpha,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HNF-4-alpha recombinant protein (Position: Q164-I474). Human HNF-4-alpha shares 95% and 96% amino acid (aa) sequence identity with mouse and rat HNF-4-alpha, respectively.
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亚型
- IgG2a
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anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 324-423) antibody
HNF4A 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4E2 unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) antibodyHNF4A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 1-464) antibodyHNF4A 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (pSer313) antibodyHNF4A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) antibodyHNF4A 适用: 小鼠 WB, IHC, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 281-312) antibodyHNF4A 适用: 人, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 1-464) antibodyHNF4A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 281-312) antibodyHNF4A 适用: 人, 大鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB17745 unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 200-300) antibodyHNF4A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) antibodyVerified HNF4A 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))
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别名
- HNF4A
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背景
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Background: Hepatocyte nuclear factor 4 alpha (HNF4A), also known as NR2A1, is a nuclear receptor that in humans is encoded by the HNF4A gene. It is mapped to 20q13.12. HNF4A is a nuclear transcription factor that binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene plays a role in development of the liver, kidney, and intestines. HNF4A is required for the PXR and CAR-mediated transcriptional activation of CYP3A4. This gene also plays a pivotal role in the expression and synthesis of SHBG, an important glycoprotein made primarily in the liver, which in addition to lowering insulin-resistance also serves in reducing levels of free Oestrogen as-well as prolonging the half-life of Testosterone.
Gene Full Name: hepatocyte nuclear factor 4 alpha
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基因ID
- 3172
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UniProt
- P41235
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途径
- AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process
抗原
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