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GCH1 抗体 (AA 1-250) (APC)

The APC-conjugated 兔 多克隆 anti-GCH1 antibody (ABIN7995566) specifically detects GCH1 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7995566
发货至: 中国
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Quick Overview for GCH1 抗体 (AA 1-250) (APC) (ABIN7995566)

抗原

See all GCH1 抗体
GCH1 (GTP Cyclohydrolase 1 (GCH1))

适用

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人, 小鼠, 大鼠

宿主

  • 60
  • 8
  • 1

克隆类型

  • 65
  • 4
多克隆

标记

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This GCH1 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    • 20
    • 15
    • 8
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
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    • 1
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    AA 1-250

    原理

    Anti-GCH1 Antibody APC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human GCH1 shares 89.2%,92.5% amino acid (aa) sequence identity with mouse,rat GCH1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GCH1 recombinant protein (Position: M1-S250). Human GCH1 shares 89.2% and 92.5% amino acid (aa) sequence identity with mouse and rat GCH1, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GCH1 (GTP Cyclohydrolase 1 (GCH1))

    别名

    GCH1

    背景

    Background: This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.

    Gene Full Name: GTP cyclohydrolase 1

    基因ID

    2643

    UniProt

    P30793
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