GCH1 抗体 (AA 1-250) (Fluoro488)
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Quick Overview for GCH1 抗体 (AA 1-250) (Fluoro488) (ABIN7995561)
抗原
See all GCH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-250
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原理
- Anti-GCH1 Antibody Fluoro488 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human GCH1 shares 89.2%,92.5% amino acid (aa) sequence identity with mouse,rat GCH1,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GCH1 recombinant protein (Position: M1-S250). Human GCH1 shares 89.2% and 92.5% amino acid (aa) sequence identity with mouse and rat GCH1, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- GCH1 (GTP Cyclohydrolase 1 (GCH1))
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别名
- GCH1
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背景
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Background: This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.
Gene Full Name: GTP cyclohydrolase 1
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基因ID
- 2643
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UniProt
- P30793
抗原
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