Growth Hormone Receptor 抗体 (Middle Region) (FITC)
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Quick Overview for Growth Hormone Receptor 抗体 (Middle Region) (FITC) (ABIN7995520)
抗原
See all Growth Hormone Receptor (GHR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-Growth hormone receptor/GHR Antibody FITC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat sequence.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of mouse Growth hormone receptor, identical to the related rat sequence.
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亚型
- IgG
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anti-Growth Hormone Receptor (GHR) (AA 101-200) antibody
GHR 适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 353-588) antibodyGHR 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 19-118) antibodyGHR 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-Growth Hormone Receptor (GHR) antibodyGHR 适用: 人 ELISA, IHC, IF 宿主: 兔 Monoclonal 10C11 unconjugated Recombinant Antibody
anti-Growth Hormone Receptor (GHR) (AA 36-266) antibodyGHR 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 315-574) antibodyGHR 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 25-650) antibodyGHR 适用: 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 19-118) antibodyGHR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 19-184) antibodyGHR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Hormone Receptor (GHR) (AA 36-85) antibodyGHR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Growth Hormone Receptor (GHR)
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别名
- GHR
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背景
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Background: The GHR locus to human chromosome 5p13.1-p12 and to mouse chromosome 15. Additionally, its gene has 9 exons that encode the receptor and several additional exons in the 5-prime untranslated region. The coding exons span at least 87 kb. GHR consists of an extracellular domain of 246 amino acids, a single transmembrane domain, and a cytoplasmic domain. Exons 3 to 7 encode the extracellular domain. There are 2 isoforms of GHR in humans, generated by retention or exclusion of exon 3 during splicing: a full-length isoform and an isoform that lacks exon 3 (d3GHR). Furthermore, the two isoforms of GHR are expressed in the placenta and appeared to be due to alternative splicing. In cirrhosis, there is a state of acquired GH resistance, as defined by high circulating GH levels with low IGF1 levels. Moreover, Mutations in the GHR gene have been demonstrated as the cause of Laron syndrome , also known as the growth hormone insensitivity syndrome (GHIS).
Gene Full Name: growth hormone receptor
Sequence Similarities: Belongs to the type I cytokine receptor family. Type 1 subfamily.
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基因ID
- 14600
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UniProt
- P16882
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途径
- NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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