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Growth Hormone Receptor 抗体 (AA 25-650) (Fluoro594)

The 兔 多克隆 anti-Growth Hormone Receptor antibody is suitable to detect Growth Hormone Receptor in samples from 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7995508
发货至: 中国
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Quick Overview for Growth Hormone Receptor 抗体 (AA 25-650) (Fluoro594) (ABIN7995508)

抗原

See all Growth Hormone Receptor (GHR) 抗体
Growth Hormone Receptor (GHR)

适用

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小鼠, 大鼠

宿主

  • 98
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克隆类型

  • 78
  • 26
多克隆

标记

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This Growth Hormone Receptor antibody is conjugated to Fluoro594

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 25-650

    原理

    Anti-Growth hormone receptor/GHR Antibody Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Growth hormone receptor/GHR recombinant protein (Position: T25-Q650).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Growth Hormone Receptor (GHR)

    别名

    Ghr

    背景

    Background: Growth hormone receptor is a protein that in humans is encoded by the GHR gene. It is mapped to 15 A1, 15 1.84 cM. This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

    Gene Full Name: growth hormone receptor

    基因ID

    14600

    UniProt

    P16882

    途径

    NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
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