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GADD45A 抗体 (C-Term) (PE)

The PE-conjugated 兔 多克隆 anti-GADD45A antibody (ABIN7995182) specifically detects GADD45A in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7995182
发货至: 中国
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Quick Overview for GADD45A 抗体 (C-Term) (PE) (ABIN7995182)

抗原

See all GADD45A 抗体
GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

适用

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宿主

  • 55
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克隆类型

  • 57
  • 6
多克隆

标记

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This GADD45A antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    • 16
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    C-Term

    原理

    Anti-GADD45A Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human GADD45A, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

    别名

    GADD45A

    背景

    Background: Growth arrest and DNA-damage-inducible protein GADD45 alpha (GADD45A) is a protein that in humans is encoded by the GADD45A gene. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. It is located on 1p34-p12. Sequence analysis of human and hamster cDNA clones demonstrated that the gene has been highly conserved and encodes a novel 165-amino acid polypeptide. Northern blot analysis detected moderate expression of a 1.4-kb GADD45A transcript in heart, skeletal muscle, and kidney, with little or no expression in brain, placenta, lung, liver, and pancreas. In addition, Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

    Gene Full Name: growth arrest and DNA damage inducible alpha

    基因ID

    1647

    UniProt

    P24522

    途径

    p53 Pathway, Cell Division Cycle
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