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GDNF 抗体 (AA 78-211) (HRP)

This 兔 多克隆 antibody specifically detects GDNF in WB, IHC 和 ELISA. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN7993296
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GDNF 抗体 (AA 78-211) (HRP) (ABIN7993296)

抗原

See all GDNF 抗体
GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

适用

  • 108
  • 70
  • 60
  • 16
  • 16
  • 1
人, 大鼠

宿主

  • 106
  • 8
  • 3
  • 2
  • 2

克隆类型

  • 91
  • 25
  • 3
多克隆

标记

  • 55
  • 12
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GDNF antibody is conjugated to HRP

应用范围

  • 88
  • 48
  • 31
  • 27
  • 13
  • 13
  • 10
  • 8
  • 6
  • 6
  • 5
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 19
    • 16
    • 12
    • 8
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 78-211

    原理

    Anti-GDNF Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human GDNF shares 93% amino acid (aa) sequence identity with both mouse,rat GDNF.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human GDNF recombinant protein (Position: S78-I211). Human GDNF shares 93% amino acid (aa) sequence identity with both mouse and rat GDNF.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

    别名

    GDNF

    背景

    Background: Glial cell line-derived neurotrophic factor (GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily. GDNF is also a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures including embryonic neuronal cultures. In addition to its potential role in the differentiation and survival of central nervous system neurons, it has profound effects on kidney organogenesis and the development of the peripheral nervous system. GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons.

    Gene Full Name: glial cell derived neurotrophic factor

    Sequence Similarities: Belongs to the TGF-beta family. GDNF subfamily.

    基因ID

    2668

    UniProt

    P39905

    途径

    RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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