Gelsolin 抗体 (AA 580-782) (Fluoro647)
Our Local Distributor
北京 101111
Quick Overview for Gelsolin 抗体 (AA 580-782) (Fluoro647) (ABIN7993046)
抗原
See all Gelsolin (GSN) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 580-782
-
原理
- Anti-Gelsolin/GSN Antibody Fluoro647 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
预测反应
- Human Gelsolin shares 94%,95% amino acid (aa) sequences identity with mouse,rat Gelsolin,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Gelsolin recombinant protein (Position: E580-A782). Human Gelsolin shares 94% and 95% amino acid (aa) sequences identity with mouse and rat Gelsolin, respectively.
-
亚型
- IgG
-
-
anti-Gelsolin (GSN) (AA 170-423) antibody
GSN 适用: Cow WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Gelsolin (GSN) (AA 577-771) antibodyGSN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gelsolin (GSN) (AA 674-782) antibodyGSN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gelsolin (GSN) (AA 673-782) antibodyGSN 适用: 人 WB, IP, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3G5 unconjugated
anti-Gelsolin (GSN) antibodyGSN 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5E3B9 unconjugated
anti-Gelsolin (GSN) (AA 543-782) antibodyGSN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Gelsolin (GSN) (AA 432-625) antibodyGSN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gelsolin (GSN) (AA 432-553) antibodyGSN 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Gelsolin (GSN) (AA 1-782) antibodyGSN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Gelsolin (GSN) (C-Term) antibodyKO Validated GSN 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- Gelsolin (GSN)
-
别名
- GSN
-
背景
-
Background: Gelsolin, also known as GNS or brevin, is an actin-binding protein that is a key regulator of actin filament assembly and disassembly. Gelsolin is one of the most potent members of the actin-severing gelsolin/villin superfamily. The gene was assigned to human chromosome 9q33.2. It is the principal intracellular and extracellular actin-severing protein. Gelsolin and Gc protein together constitute the extracellular actin-scavenger system which prevents the toxic effects of actin release into the extracellular space under circumstances of cell necrosis. Gelsolin may have therapeutic potential as a mucolytic agent in CF patients. The antiapoptotic activity of gelsolin seems to prevent a step leading to cytochrome c release from the mitochondria into the cytosol.
Gene Full Name: gelsolin
Sequence Similarities: Belongs to the villin/gelsolin family.
-
基因ID
- 2934
-
UniProt
- P06396
-
途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
抗原
-
