FLT4 抗体 (AA 25-259) (HRP)
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Quick Overview for FLT4 抗体 (AA 25-259) (HRP) (ABIN7991266)
抗原
See all FLT4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-259
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原理
- Anti-VEGF Receptor 3/FLT4 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human VEGF Receptor 3 recombinant protein (Position: Y25-N259).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
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别名
- FLT4
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背景
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Background: Fms-related tyrosine kinase 4, also known as FLT4 or VEGFR3, is a protein which in humans is encoded by the FLT4 gene. It is mapped to 5q35.3. This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. FLT4 has an essential role in the development of the embryonic cardiovascular system before the emergence of the lymphatic vessels. It has been found that FLT4, which provides proangiogenic signaling when expressed on endothelium, may also have antiangiogenic properties when expressed at an avascular site by nonendothelial cells. FLT4 is also regarded as a regulator of vascular network formation.
Gene Full Name: fms related receptor tyrosine kinase 4
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基因ID
- 2324
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UniProt
- P35916
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
抗原
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