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FLT4 抗体

FLT4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H4 unconjugated
产品编号 ABIN969147
发货至: 中国
  • 抗原 See all FLT4 抗体
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    适用
    • 73
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    宿主
    • 67
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    小鼠
    克隆类型
    • 68
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    单克隆
    标记
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    This FLT4 antibody is un-conjugated
    应用范围
    • 52
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    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human FLT4 expressed in E. coli.
    克隆位点
    4H4
    亚型
    IgG1
    Top Product
    Discover our top product FLT4 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Goodyear, Kheyfets, Garcia, Stearns: "Role of the VEGFR3/VEGFD receptor axis in TGFbeta1 activation of primary prostate cell lines." in: The Prostate, Vol. 69, Issue 9, pp. 982-90, (2009) (PubMed).

    Pan, Chang, Chang, Su, Wang, Hung: "Sumoylation of Prox1 controls its ability to induce VEGFR3 expression and lymphatic phenotypes in endothelial cells." in: Journal of cell science, Vol. 122, Issue Pt 18, pp. 3358-64, (2009) (PubMed).

    Jayasinghe, Simiantonaki, Michel-Schmidt, Kirkpatrick: "Endothelial VEGFR-3 expression in colorectal carcinomas is associated with hematogenous metastasis." in: Oncology reports, Vol. 22, Issue 5, pp. 1093-100, (2009) (PubMed).

  • 抗原
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    别名
    FLT4 (FLT4 产品)
    别名
    FLT41 antibody, LMPH1A antibody, PCL antibody, VEGFR3 antibody, AI323512 antibody, Chy antibody, Flt-4 antibody, VEGFR-3 antibody, Vegfr3 antibody, cb1059 antibody, fms related tyrosine kinase 4 antibody, FMS-like tyrosine kinase 4 antibody, fms-related tyrosine kinase 4 antibody, FLT4 antibody, Flt4 antibody, flt4 antibody
    背景

    Description: This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. Tissue specificity: Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain. VEGFR-3 is induced in all endothelial cells (EC's) during early embryogenesis, and its expression eventually disappears from the vascular endothelial cells of adult tissues. VEGFR-3 is constitutively expressed in the adult lymphatic endothelium. Although VEGFR-3 is not expressed in adult blood vessels, it is induced in vascular endothelial cells of tumor-bearing tissues.VEGFR-3 expression in adults is largely restricted to the endothelial cells of the lymphatic system, and high endothelial venules (HEV).

    Aliases: PCL, FLT41, LMPH1A, VEGFR3, FLT4

    分子量
    145 kDa
    基因ID
    2324
    HGNC
    2324
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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