FLT1 抗体 (AA 27-73)
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北京 101111
Quick Overview for FLT1 抗体 (AA 27-73) (ABIN7991160)
抗原
See all FLT1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 27-73
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原理
- Anti-VEGFR-1/FLT1 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human FLT1 shares 78.7%,81.8% amino acid (aa) sequence identity with mouse,rat FLT1,respectively.
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产品特性
- Anti-VEGFR-1/FLT1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human VEGFR-1/FLT1 recombinant protein (Position: S27-R73). Human FLT1 shares 78.7% and 81.8% amino acid (aa) sequence identity with mouse and rat FLT1, respectively.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
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别名
- FLT1
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背景
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Background: Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Gene Full Name: fms related receptor tyrosine kinase 1
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分子量
- 200 kDa
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基因ID
- 2321
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UniProt
- P17948
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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