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FLT1 抗体 (AA 27-73) (Fluoro647)

The Fluoro647-conjugated 兔 多克隆 anti-FLT1 antibody (ABIN7991159) specifically detects FLT1 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7991159
发货至: 中国
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Quick Overview for FLT1 抗体 (AA 27-73) (Fluoro647) (ABIN7991159)

抗原

See all FLT1 抗体
FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FLT1 antibody is conjugated to Fluoro647

应用范围

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Flow Cytometry (FACS)
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    AA 27-73

    原理

    Anti-VEGFR-1/FLT1 Antibody Fluoro647 Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human FLT1 shares 78.7%,81.8% amino acid (aa) sequence identity with mouse,rat FLT1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human VEGFR-1/FLT1 recombinant protein (Position: S27-R73). Human FLT1 shares 78.7% and 81.8% amino acid (aa) sequence identity with mouse and rat FLT1, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

    别名

    FLT1

    背景

    Background: Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

    Gene Full Name: fms related receptor tyrosine kinase 1

    基因ID

    2321

    UniProt

    P17948

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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