Flotillin 2 抗体 (AA 169-344) (Cy3)
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Quick Overview for Flotillin 2 抗体 (AA 169-344) (Cy3) (ABIN7991107)
抗原
See all Flotillin 2 (FLOT2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 169-344
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原理
- Anti-Flotillin 2 Antibody (monoclonal, 4D8A3) Cy3 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- Human Flotillin 2 shares 100% amino acid (aa) sequence identity with both,rat Flotillin 2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Flotillin 2 recombinant protein (Position: K169-K344). Human Flotillin 2 shares 100% amino acid (aa) sequence identity with both and rat Flotillin 2.
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亚型
- IgG2b
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Flotillin 2 (FLOT2)
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别名
- FLOT2
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背景
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Background: FLOT2 (Flotillin 2), also known as ESA1 or M17S1, is a protein that in humans is encoded by the FLOT2 gene. Schroeder et al. (1991) isolated a cDNA for an epidermal surface antigen believed to be involved in epidermal cell adhesion. By analysis of a somatic cell hybrid panel and in situ hybridization using the ESA cDNA, the gene was mapped to 17q11-q12 in the region containing the NF1 gene. Bickel et al. (1997) found that Flot2 consistently copurifies with Flot1 and with caveolin-1 in the purification of caveolin-rich membranes. Using a quantitative proteomic analysis of cultured neuronal stem cells, Li et al. (2012) found that palmitoylation and oligomerization of flotillin-2 was abolished in homozygous Dhhc5 mutant neuronal stem cells. The absolute amount of flotillin-2 was not changed in Dhhc5 mutant neurons.
Gene Full Name: flotillin 2
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基因ID
- 2319
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UniProt
- Q14254
抗原
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